Human-Induced Pluripotent Stem Cell-Derived Cardiomyocyte Model for TNNT2 Δ160E-Induced Cardiomyopathy.
Takumi KondoShuichiro HigoMikio ShibaYasuaki KohamaSatoshi KamedaTomoka TabataHiroyuki InoueShota OkunoShou OgawaSatoki NakamuraMaki TakedaEmiko ItoJunjun LiLi LiuYuki KuramotoJong-Kook LeeSeiji TakashimaShigeru MiyagawaYoshiki SawaShungo HikosoYasushi SakataPublished in: Circulation. Genomic and precision medicine (2022)
Δ160E mutation and can serve as a human model for therapeutic development to prevent hypertrophic cardiomyopathy pathology.