Plasminogen activator inhibitor 1 is a novel faecal biomarker for monitoring disease activity and therapeutic response in inflammatory bowel diseases.

Boldizsár JójártTamás ResálDiána KataTünde MolnárPéter BacsurViktória SzabóÁrpád VargaKata Judit SzántóPetra PallagiImre FöldesiTamás MolnárJózsef MaléthKlaudia Farkas

Published in: Journal of Crohn's & colitis (2023)

The serum, mucosal, and faecal PAI-1 concentration correlates with the disease activity and therapeutic response in IBD, suggesting that PAI-1 could be utilized as a novel non-invasive, disease-specific faecal biomarker in the patient follow-up.

Keyphrases

disease activity
systemic lupus erythematosus
rheumatoid arthritis
rheumatoid arthritis patients
ankylosing spondylitis
juvenile idiopathic arthritis
case report
ulcerative colitis