Astragalin Inhibits Nuclear Factor-κB Signaling in Human Colonic Epithelial Cells and Attenuates Experimental Colitis in Mice.

Yoo Min Han Jaemoon Koh Jee Hyun Kim Jooyoung Lee Jong-Pil Im Joo Sung Kim

Published in: Gut and liver (2021)

Astragalin exerted an anti-inflammatory effect through NF-κB pathway inhibition and attenuated murine colitis. Astragalin is thus a potential therapeutic agent for IBD.

Keyphrases

nuclear factor
ulcerative colitis
toll like receptor
anti inflammatory
endothelial cells
induced pluripotent stem cells
pluripotent stem cells
high fat diet induced
signaling pathway
inflammatory response
oxidative stress
metabolic syndrome
pi k akt
skeletal muscle