GLP-1 signaling-regulated SNAP25 is involved in improved insulin secretion in diabetic GK rats after Roux-en-Y gastric bypass surgery.
Xiangchen KongChao LinChenxi YangXin WangBingfeng LiDan YanYanhui YangAnyi HuYanyin ChenXiaohui XuXiaosong MaPublished in: Molecular biology reports (2024)
Our findings unravel the novel mechanisms of RYGB-enhanced SNAP25 expression in β-cells, and SNAP25 may contribute to the improved β-cell secretory function induced by RYGB.
Keyphrases
- roux en y gastric bypass
- weight loss
- gastric bypass
- obese patients
- induced apoptosis
- minimally invasive
- poor prognosis
- single cell
- bariatric surgery
- cell cycle arrest
- type diabetes
- coronary artery bypass
- transcription factor
- cell therapy
- oxidative stress
- stem cells
- long non coding rna
- acute coronary syndrome
- bone marrow
- percutaneous coronary intervention
- coronary artery disease
- pi k akt
- atrial fibrillation