Validated Microwell-Based Spectrofluorimetric Method for Quantification of Ravidasvir (New Anti-Chronic Hepatitis C Virus-GT4) in Rat Plasma and Its Application to Pharmacokinetic Study.
Mohamed M HefnawyMona Al-ShehriSara Al-RashoodSherif HammadMohammed AlanaziNawaf A AlsaifMostafa MohammedAhmad ObaidullahManal El-GendyPublished in: Drug design, development and therapy (2020)
The approved technique was effectively applied for a pharmacokinetic (PK) study after single oral gavage administration of RAV at a dose of 35 mg/kg and it could be presumed that the proposed assay can be applied to clinical trials.