Loss of testosterone induces postprandial insulin resistance and increases the expression of the hepatic antioxidant flavin-containing monooxygenases in mice exposed to intermittent hypoxia.
Gauthier Ganouna-CohenFrançois MarcouillerBritanny Blachot-MinassianMaud DemarestCharles Joly BeauparlantArnaud DroitElise BelaidiAida BairamVincent JosephPublished in: Acta physiologica (Oxford, England) (2024)
Low levels of testosterone in male mice exposed to IH induce post-prandial hyperinsulinemia and insulin resistance and determine the mechanisms by which the liver handles IH-induced oxidative stress.
Keyphrases
- insulin resistance
- high fat diet induced
- replacement therapy
- adipose tissue
- metabolic syndrome
- high fat diet
- polycystic ovary syndrome
- skeletal muscle
- poor prognosis
- type diabetes
- oxidative stress
- hydrogen peroxide
- blood glucose
- endothelial cells
- anti inflammatory
- binding protein
- glycemic control
- smoking cessation
- long non coding rna