Neural stem/progenitor cell therapy for Alzheimer disease in preclinical rodent models: a systematic review and meta-analysis.

Zijing ZhouBen ShiYaxing XuJinyu ZhangXin LiuXinghong ZhouBaofeng FengJun MaHuixian Cui

Published in: Stem cell research & therapy (2023)

Our results suggested that NSPC therapy could improve the cognitive function and slow down the progression of AD. Due to the limitations of models, more animal trials and clinical trials are needed.

Keyphrases

clinical trial
mild cognitive impairment
cell therapy
stem cells
randomized controlled trial
phase ii
mesenchymal stem cells
study protocol