Effect of the 1-h bundle on mortality in patients with suspected sepsis in the emergency department: a stepped wedge cluster randomized clinical trial.
Yonathan FreundMarta Cancella de AbreuSoufiane LebalAlexandra RousseauThomas LafonYouri YordanovRichard MacrezFabien CoisyPierrick Le BorgneFlorent FemyDelphine DouilletNeus Robert BoterXavier EyerJean-Baptiste Bouillon-MinoisCarl OgereauDonia BouzidHélène GouletMélanie RousselGeoffroy RousseauJeremy GuénézanCeline OccelliTahar ChouihedGina Osorio QuispeMarine Clea RenardJudith GorlickiBen BloomTabassome SimonCamille GerlierPublished in: Intensive care medicine (2024)
Among patients with suspected sepsis in the ED, the implementation of the 1-h sepsis bundle was not associated with significant difference in in-hospital mortality. However, this study may be underpowered to report a statistically significant difference between groups.