Melittin Inducing the Apoptosis of Renal Tubule Epithelial Cells through Upregulation of Bax/Bcl-2 Expression and Activation of TNF-α Signaling Pathway.

Ying ShuYingying YangYuliang ZhaoLiang MaPing FuTiantian WeiLing Zhang

Published in: BioMed research international (2019)

Melittin can lead to the apoptosis of RTECs, which may be mediated by upregulating the expression of Bax/Bcl-2 and activating the TNF-α signaling pathway.

Keyphrases

signaling pathway
induced apoptosis
poor prognosis
pi k akt
endoplasmic reticulum stress
cell cycle arrest
oxidative stress
rheumatoid arthritis
epithelial mesenchymal transition
cell death
long non coding rna
binding protein