CCN3 is dynamically regulated by treatment and disease state in multiple sclerosis.

Michelle NaughtonJill MoffatGeorge EleftheriadisNira de la Vega GallardoAndrew YoungJohn FalconerKristen HawkinsBen PearsonBernard PerbalAndrew HoganPaul MoynaghSam LovelessNeil P RobertsonBruno GranRachael KeeStella HughesGavin McDonnellOwain HowellDenise C Fitzgerald

Published in: Journal of neuroinflammation (2020)

This investigation provides the first comprehensive profile of CCN3 expression in MS and provides rationale to determine if CCN3 contributes to neuroimmunological functions in the CNS.

Keyphrases

multiple sclerosis
poor prognosis
mass spectrometry
ms ms
clinical trial
blood brain barrier
white matter
binding protein
long non coding rna
combination therapy
smoking cessation