Analysis of the Efficacy and Mechanism of Action of Xuebijing Injection on ARDS Using Meta-Analysis and Network Pharmacology.
Yun ZhangJie WangYong-Mei LiuHui YangGuang-Jun WuXuan-Hui HePublished in: BioMed research international (2021)
Our results recommended Xuebijing treatment for patients with ARDS. Xuebijing has therapeutic effects on ARDS patients partly by regulating the immune cell/cytokine pathways and thus inhibiting the cytokine storm. TNF-α is the cytokine both directly and indirectly inhibited by Xuebijing, and IL-6 is the cytokine mainly indirectly inhibited by Xuebijing.
Keyphrases
- acute respiratory distress syndrome
- extracorporeal membrane oxygenation
- systematic review
- end stage renal disease
- mechanical ventilation
- chronic kidney disease
- newly diagnosed
- rheumatoid arthritis
- prognostic factors
- signaling pathway
- peritoneal dialysis
- randomized controlled trial
- meta analyses
- patient reported outcomes
- replacement therapy
- case control