A simian-adenovirus-vectored rabies vaccine suitable for thermostabilisation and clinical development for low-cost single-dose pre-exposure prophylaxis.
Chuan WangPawan DulalXiangyang ZhouZhiquan XiangHooman GoharrizAshley BanyardNicky GreenLivia BrunnerRoland VenturaNicolas CollinSimon J DraperAdrian V S HillRebecca AshfieldAnthony R FooksHildegund C ErtlAlexander D DouglasPublished in: PLoS neglected tropical diseases (2018)
ChAdOx2 RabG may prove to be a useful tool to reduce the human rabies death toll. We have secured funding for Good Manufacturing Practice- compliant bio-manufacture and Phase I clinical trial of this candidate.