Impact of left ventricle outflow tract calcification on the outcomes of transcatheter aortic valve implantation: A study-level meta-analysis.
Michel Pompeu Barros Oliveira SáJef Van den EyndeJohn H MalinGianluca TorregrossaSerge SicouriBasel RamlawiPublished in: Journal of cardiac surgery (2022)
The presence of significant LVOT calcification increases the risk of periprocedural and 1-year mortality, stroke, myocardial infarction, PVL and aortic annulus/root rupture after TAVI. Self-expandable valves may be a preferrable option in this scenario. Structural heart surgeons and interventional cardiologists should consider this factor when referring patients for TAVI and technical aspects (such as the type of transcatheter heart valve to be deployed or the use of pre-/post-dilatation) should be factored in.
Keyphrases
- aortic valve
- transcatheter aortic valve implantation
- aortic stenosis
- aortic valve replacement
- transcatheter aortic valve replacement
- ejection fraction
- end stage renal disease
- chronic kidney disease
- heart failure
- systematic review
- atrial fibrillation
- left ventricular
- newly diagnosed
- prognostic factors
- peritoneal dialysis
- randomized controlled trial
- cardiovascular events
- patient reported outcomes
- percutaneous coronary intervention
- quality improvement
- metabolic syndrome
- skeletal muscle
- adipose tissue
- type diabetes
- risk factors
- coronary artery disease
- blood brain barrier
- patient reported
- insulin resistance
- aortic dissection