Controversy and Consensus on the Management of Elevated Sperm DNA Fragmentation in Male Infertility: A Global Survey, Current Guidelines, and Expert Recommendations.
Ala'a FarkouhAshok AgarwalTaha Abo-Almagd Abdel-Meguid HamodaParviz K KavoussiRamadan SalehArmand ZiniMohamed ArafaAhmed M HarrazMurat GulVilvapathy Senguttuvan KarthikeyanDamayanthi DurairajanayagamAmarnath RambhatlaFlorence BoitrelleEric ChungPonco BirowoTuncay ToprakRamy Abou GhaydaRossella CannarellaNguyen Ho Vinh PhuocFotios DimitriadisGiorgio Ivan RussoIoannis SokolakisTaymour MostafaKonstantinos MakarounisImad ZiouziouShinnosuke KurodaMarion BendayanRaneen Sawaid KaiyalAndrian JapariSimopoulou MaraLucia RoccoNicolás GarridoNazim GherabiKadir BöcüOguzhan KahramanTan V LeChristine WynsKelton P TremellenSelçuk SarikayaSheena E M LewisDonald P EvensonEdmund Y KoAldo Eugenio CalogeroFahmi BaharMarlon P MartinezAndrea CrafaNguyen QuangRafael Favero AmbarGiovanni M Colpi ForumMustafa Emre BakırcıoğluRalf Reinhold HenkelHussein KandilEge Can ŞerefoğluAbdullah AlfakhriAkira TsujimuraAlireza KheradmandChristina AnagnostopoulouAngelo MarinoAram AdamyanBirutė ŽilaitienėCevahir OzerEdoardo PescatoriParaskevi VogiatziGian Maria BusettoGiancarlo BalerciaHaitham ElBardisiHamed AkhavizadeganMohammad Ali Sadighi GilaniHisanori TaniguchiHyun Jun ParkIsrael Maldonado RosasMohamed S Al-MarhoonMohammad Ali Sadighi GilaniNaif AlhathalGermar-Michael PinggeraPriyank KothariNasser MogharabianSava MicicSheryl T HomaSara DarbandiTran Quang Tien LongWael ZohdyWidi AtmokoMarjan SabbaghianWael IbrahimRyan P SmithChristopher Chee Kong HoJean J M C H de la RosetteAhmed I El-SakkaMirko PretoCătălina BarbăroșieSaad Mohammed AbumelhaAykut BaşerKaan AydosLiliana Ramirez-DominguezVijay KumarTeng-Aik OngTiago Cesar MierzwaRicky AdriansjahSaleem Ali BanihaniKasonde BowaShinichiro FukuharaMarcelo Gabriel Rodriguez PeñaMohamad A MoussaUmut Çağın AriChak-Lam ChoNicholas N TadrosMuhammet Rasit UgurEdouard AmarFalcone MarcoFrederic Romain SanterArif KalkanlıKeshab Kumar KarnaKareim KhalafallaRanjit B VishwakarmaFederica FinocchiCarlo GiulioniErman CeyhanGökhan ÇekerChadi YazbeckOsvaldo RajmilMehmet YılmazBaris AltayTrenton L BarrettKay Seong NgooShubhadeep RoychoudhuryGianmaria SalvioHao-Cheng LinAtes KadiogluMassimiliano TimpanoTomer Avidor-ReissLukman HakimPuneet SindhwaniGiorgio FrancoRajender SinghFilippo GiaconeMikhail RuzaevRaghavender KosgiNikolaos SofikitisAyad PalaniGökhan ÇalıkDeniz KulaksızDavor JezekManaf Al HashimiPanagiotis DrakopoulosHuda Mossa OmranSofia LeonardiCiler Celik-OzenciNur Dokuzeylul GungorJonathan W RamsayToshiyasu AmanoEmrullah SogutdelenGede Wirya Kusuma DuarsaKoji ChibaSunil K JindalMissy SaviraLuca BoeriEdson BorgesDeepak GupteFatih GokalpGuadalupe Hernández HebrardSukhbinder MinhasRupin Shahnull nullPublished in: The world journal of men's health (2023)
This paper presents the results of a large global survey on the management of infertile men with elevated SDF and reveals a lack of consensus among clinicians. Furthermore, it demonstrates the scarcity of professional society guidelines in this regard and attempts to highlight the relevant evidence. Expert recommendations are proposed to help guide clinicians.