Impact of Comorbid Affective Disorders on Longitudinal Clinical Outcomes in Individuals at Ultra-high Risk for Psychosis.
Frederike SchirmbeckNadine C van der BurgMatthijs BlankersJentien M VermeulenPhilip McGuireLucia R ValmaggiaMatthew J KemptonMark van der GaagAnita Riecher-RösslerRodrigo A BressanNeus Barrantes-VidalBarnaby NelsonG Paul AmmingerPatrick McGorryChristos PantelisMarie-Odile KrebsStephan RuhrmannGabriele SachsBart P F RuttenJim van OsMerete NordentoftBirte Glenthøjnull nullPaolo Fusar-PoliLieuwe de HaanPublished in: Schizophrenia bulletin (2021)
A past depressive episode might be a particularly relevant risk factor for an unfavorable course of APS in UHR individuals. Early affective disturbances may be used to advance detection, prognostic, and clinical strategies.