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Drug Retention Rates of Janus Kinase Inhibitors in Rheumatoid Arthritis Patients with Therapy-Induced Lymphopenia.

Jumpei TemmokuMasayuki MiyataEiji SuzukiYuya SumichikaKenji SaitoShuhei YoshidaHaruki MatsumotoYuya FujitaNaoki MatsuokaTomoyuki AsanoShuzo SatoHiroshi WatanabeKiyoshi Migita
Published in: Journal of clinical medicine (2023)
These findings suggest that lymphopenia during the first 4 months from the initiation of JAKi is associated with reduced drug retention rates in patients with RA due to AEs, which is exclusively associated with the use of tofacitinib.
Keyphrases
  • rheumatoid arthritis patients
  • disease activity
  • rheumatoid arthritis
  • drug induced
  • high glucose
  • ankylosing spondylitis
  • stem cells
  • endothelial cells
  • bone marrow