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Nicotinamide N-methyltransferase expression and its association with phospho-Akt, p53 expression, and survival in high-grade endometrial cancer

Serra Akarİsmail HarmankayaSerdar UğraşCetin Celik
Published in: Turkish journal of medical sciences (2019)
This study suggests that NNMT may promote cancer progression and that NNMT overexpression is associated with aberrant p53 expression, pAkt, and poor survival. NNMT’s role in cancer progression could make it a target of EC therapy.
Keyphrases
  • poor prognosis
  • endometrial cancer
  • high grade
  • papillary thyroid
  • cell proliferation
  • squamous cell
  • long non coding rna
  • signaling pathway
  • stem cells
  • low grade
  • squamous cell carcinoma
  • bone marrow