Platelet inhibitor withdrawal and outcomes after coronary artery surgery: an individual patient data meta-analysis.
Michael SchoerghuberThomas KuenzerFausto BiancariMagnus DalénEmma C HanssonAnders JeppssonGeorg SchlachtenbergerMartin SiegemundAndreas VoetschGudrun PregartnerInes LindenauDaniel ZimpferAndrea BergholdElisabeth MahlaAndreas ZirlikPublished in: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery (2024)
Guideline-conforming preoperative withdrawal of ticagrelor and clopidogrel was associated with a 50% reduced BARC-4 bleeding risk when corrected for EuroSCORE II and cardiopulmonary bypass time but was not associated with increased risk of 30-day mortality or postoperative ischaemic events.
Keyphrases
- coronary artery
- acute coronary syndrome
- percutaneous coronary intervention
- systematic review
- coronary artery bypass
- patients undergoing
- antiplatelet therapy
- minimally invasive
- pulmonary artery
- st segment elevation myocardial infarction
- meta analyses
- atrial fibrillation
- st elevation myocardial infarction
- cardiovascular events
- case report
- electronic health record
- coronary artery disease
- big data
- risk factors
- case control
- surgical site infection
- cardiovascular disease
- randomized controlled trial
- artificial intelligence
- type diabetes