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Tuberculosis Diagnosis and Preventive Monotherapy Among Children and Adolescents Exposed to Rifampicin-Resistant Tuberculosis in the Household.

Ivy ApolisiHelen CoxNolitha TyekuJohnny DanielsShaheed MatheeRabia CariemBianca Douglas-JonesNoluvo NgambuVanessa MudalyErika Mohr-HollandPetros IsaakidisColin PfaffJennifer FurinAnja Reuter
Published in: Open forum infectious diseases (2023)
Post-MDR/RR-TB exposure management for children and adolescents resulted in significant MDR/RR-TB detection and both high TPT initiation and completion. Tuberculosis preventive monotherapy was well tolerated and there were no further TB diagnoses after initial assessment. Key factors supporting these outcomes included use of pediatric formulations for young children, monotherapy, and community-based options for assessment and follow up.
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