Hypoxia induced changes in miRNAs and their target mRNAs in extracellular vesicles of esophageal squamous cancer cells.

Fangyu ChenLi ChuJie LiYu ShiBing XuJunjie GuXijuan YaoMeng TianXi Yang Xin-Chen Sun

Published in: Thoracic cancer (2020)

This study, for the first time reveals changes in the expression of exosomal miRNAs in hypoxic ESCC cells and these findings will act as a resource to study the hypoxic tumor microenvironment and ESCC EVs.

Keyphrases

poor prognosis
induced apoptosis
endothelial cells
high grade
oxidative stress
cell proliferation
long non coding rna