Impact of Early Diagnostic and Therapeutic Interventions and Clinical Course in Children and Adolescents with Multiple Endocrine Neoplasia Types 1 and 2.
Ja Hye KimYena LeeSoojin HwangJi-Hee YoonGu-Hwan KimHan-Wook YooJin Ho ChoiPublished in: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association (2023)
This study described the relatively long clinical course of pediatric MEN with mean follow-up duration of 7.5 ± 3.8 years. Insulinoma was the first manifestation in children with MEN1. Early diagnosis by family screening during the asymptomatic period enabled early intervention. The patient with MEN2B exhibited the most aggressive clinical course.