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MEIS2 suppresses breast cancer development by downregulating IL10.

Yongzhi XiaoYingzhe LiuYangqing SunChanghao HuangShangwei Zhong
Published in: Cancer reports (Hoboken, N.J.) (2024)
Our study demonstrates that the tumor suppressor of MEIS2 in breast cancer progression is partially via down regulating the expression of IL10 and promoting myeloid cells infiltration. Targeting MEIS2 would be a potentially therapeutic avenue for BC.
Keyphrases
  • induced apoptosis
  • poor prognosis
  • signaling pathway
  • cell cycle arrest
  • dendritic cells
  • acute myeloid leukemia
  • cancer therapy
  • endoplasmic reticulum stress
  • oxidative stress
  • immune response
  • drug delivery
  • young adults