Comprehensive genetic analysis of histological components of combined small cell carcinoma.

Yuko IidaYoko NakanishiTetsuo ShimizuMasayuki NomotoYoshiko NakagawaReiko ItoNoriaki TakahashiShinobu MasudaYasuhiro Gon

Published in: Thoracic cancer (2022)

We conclude that the morphological evolution of heterogeneous histological components in cSCLC may be associated with differences in ASCL1 expression levels, but not in acquired somatic gene mutations.

Keyphrases

poor prognosis
copy number
binding protein
long non coding rna
dna methylation