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Dual molecule targeting HDAC6 leads to intratumoral CD4+ cytotoxic lymphocytes recruitment through MHC-II upregulation on lung cancer cells.

Sarah DucellierMélanie DemeulesBoris LetribotMassimiliano GaetaniChloé MichaudelHarry SokolAbdallah HamzeMouad AlamiMégane NascimentoSebastien Apcher
Published in: Journal for immunotherapy of cancer (2024)
cytotoxic T cell-mediated antitumor response in vivo in our model of lung cancer. This breakthrough suggests the potential of QAPHA as a promising agent for cancer treatment.
Keyphrases
  • poor prognosis
  • peripheral blood
  • cell proliferation
  • cancer therapy
  • signaling pathway
  • human health
  • long non coding rna