Premalignant Progression in the Lung: Knowledge Gaps and Novel Opportunities for Interception of Non-Small Cell Lung Cancer. An Official American Thoracic Society Research Statement.
Seyed Javad MoghaddamSociety DocumentSoni Savai PullamsettiRamin Salehi-RadShreoshi SenguptaMichael N KammerPierre MassionJennifer E BeaneEdwin J OstrinCarmen PrioloMeredith A TennisLaura P StabileAlison K BauerCatherine R SearsEva SzaboM Patricia RiveraCharles A PowellHumam KadaraBrendan J JenkinsSteven M DubinettA McGarry HoughtonCarla F KimRobert L KeithPublished in: American journal of respiratory and critical care medicine (2024)
The identified gaps in knowledge about the biological mechanisms of premalignant progression in the lung, along with ongoing challenges in screening, detection, and early intervention, highlight the critical need to prioritize research in this domain. Such focused investigations are essential to devise effective preventive strategies that may ultimately decrease lung cancer incidence and improve patient outcomes.