Combination of Pioglitazone and Metformin Actions on Liver Lipid Metabolism in Obese Mice.

Jieying LiuDongmei WangZiyan XieLu DingShunhua LiXuemei MaJing LiuJing RenCheng XiaoChunru YangXinhua Xiao

Published in: Biomolecules (2023)

Pioglitazone and metformin might have a synergistic protective effect on NAFLD by improving hepatic lipid profiles in HFD-induced mice. Further studies are needed to verify the clinical effects.

Keyphrases

high glucose
fatty acid
high fat diet
high fat diet induced
cancer therapy
case control
type diabetes
adipose tissue
oxidative stress
insulin resistance
metabolic syndrome
drug delivery
wild type