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A Single-Arm, Open-Label Phase II Study of ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma.

Sarah L P AtkinsYoshimi Endo GreerSarah JenkinsMargaret E Gatti-MaysNicole HoustonSunmin LeeMin-Jung LeeShraddha RastogiNahoko SatoChristina BurksChristina M AnnunziataJung-Min LeeKunio NagashimaJane B TrepelStanley LipkowitzAlexandra S Zimmer
Published in: The oncologist (2023)
ONC201 monotherapy did not induce objective responses in recurrent or refractory metastatic breast or endometrial cancer at the RP2D dose of 625 mg weekly but had an acceptable safety profile (ClinicalTrials.gov Identifier: NCT03394027).
Keyphrases
  • endometrial cancer
  • open label
  • phase ii study
  • metastatic breast cancer
  • phase ii
  • clinical trial
  • phase iii
  • study protocol
  • squamous cell carcinoma
  • small cell lung cancer
  • locally advanced
  • randomized controlled trial