Effect of Scalp Nerve Block Combined with Intercostal Nerve Block on the Quality of Recovery in Patients with Parkinson's Disease after Deep Brain Stimulation: Protocol for a Randomized Controlled Trial.
Ying ShengHui WangXinning ChangPeipei JinShengwei LinShuang QianJian XieWenbin LuXiya YuPublished in: Brain sciences (2022)
To explore the effect, we have designed a randomized controlled trial in which 88 patients with PD will be randomly assigned to either an SNB group or control group, receiving either SNB combined with ICNB or without before surgery. The primary outcome will be a 15-item QoR score at 24 h after surgery. The secondary outcomes will include: 15-item QoR scores at 72 h and 1 month after surgery; the numeric rating scale pain scores before discharge from the postanesthesia care unit (PACU) at 24 h, 72 h, and 1 month after surgery; rescue analgesics; nausea and vomiting 24 h after operation and remifentanil consumption during operation; emergence agitation; the duration of anesthesia and surgery; time to respiratory recovery, time to response, and time to extubation; the PACU length of stay; as well as adverse events. Proposed protocol and conclusion: Our findings will provide a novel method for the management of recovery and acute pain after DBS in PD patients. This research was registered at clinicaltrials.gov NCT05353764 on 19 April 2022.
Keyphrases
- deep brain stimulation
- minimally invasive
- parkinson disease
- chronic pain
- pain management
- coronary artery bypass
- obsessive compulsive disorder
- end stage renal disease
- neuropathic pain
- ejection fraction
- healthcare
- newly diagnosed
- respiratory failure
- randomized controlled trial
- quality improvement
- cardiac surgery
- liver failure
- prognostic factors
- acute kidney injury
- peritoneal dialysis
- type diabetes
- postoperative pain
- mechanical ventilation
- spinal cord injury
- coronary artery disease
- intensive care unit
- acute coronary syndrome
- health insurance