Protoporphyrin IX (PpIX) Fluorescence during Meningioma Surgery: Correlations with Histological Findings and Expression of Heme Pathway Molecules.
Dorothee C SpilleEva C BunkChristian ThomasZeynep ÖzdemirAndrea WagnerBurak Han AkkurtManoj MannilWerner PaulusOliver M GrauerWalter StummerVolker SennerBenjamin BrokinkelPublished in: Cancers (2023)
FGR enables the intraoperative identification of meningioma tissue with limitations concerning dura invasion and due to ectopic expression in the CNS. ABCB6, ABCG2, FECH and CPOX are expressed in meningioma tissue and are related to fluorescence.