Anti-tuberculosis chemotherapy alters TNFR2 expression on CD4+ lymphocytes in both drug-sensitive and -resistant tuberculosis: however, only drug-resistant tuberculosis maintains a pro-inflammatory profile after a long time.
Norma A Téllez-NavarreteLucero A Ramon-LuingMarcela Muñoz-TorricoMario Preciado-GarcíaKaren Medina-QueroRogelio Hernandez-PandoLeslie Chavez GalanPublished in: Molecular medicine (Cambridge, Mass.) (2021)
These results partially explain the differences in the immune response of DS-TB vs DR-TB. The frequency of actCD4+ tmTNFR2+ cells and inflammatory status should be considered in the follow-up of therapy in DR-TB patients.
Keyphrases
- mycobacterium tuberculosis
- drug resistant
- immune response
- pulmonary tuberculosis
- multidrug resistant
- end stage renal disease
- hiv aids
- induced apoptosis
- acinetobacter baumannii
- newly diagnosed
- chronic kidney disease
- ejection fraction
- poor prognosis
- adverse drug
- prognostic factors
- oxidative stress
- cell cycle arrest
- editorial comment
- peritoneal dialysis
- peripheral blood
- emergency department
- radiation therapy
- inflammatory response
- cell death
- human immunodeficiency virus
- patient reported outcomes
- antiretroviral therapy
- cystic fibrosis
- patient reported