Interleukin-33/ST2 signaling contributes to the severity of hemolytic uremic syndrome induced by enterohemorrhagic Escherichia coli.
Shimpei YamadaMasaki ShimizuMondo KurodaNatsumi InoueNaotoshi SugimotoAkihiro YachiePublished in: Clinical and experimental nephrology (2018)
Our results indicate that IL-33 contributes to the severity of EHEC-induced HUS. Serum sST2 level in HUS patients correlated with disease activity, which suggests its potential role as a marker for disease activity and development of encephalopathy in patients with EHEC-induced HUS.
Keyphrases
- disease activity
- systemic lupus erythematosus
- rheumatoid arthritis
- rheumatoid arthritis patients
- ankylosing spondylitis
- escherichia coli
- juvenile idiopathic arthritis
- high glucose
- diabetic rats
- end stage renal disease
- ejection fraction
- newly diagnosed
- patient reported outcomes
- cystic fibrosis
- case report
- klebsiella pneumoniae