The Expression of Dectin-1, Irak1 and Rip2 During the Host Response to Aspergillus fumigatus.
Jinguo LiuLin YuCuicui ChenJian ZhouXin GongDandan LiDongni HouYuanlin SongChangzhou ShaoPublished in: Mycopathologia (2017)
Our findings demonstrate that Dectin-1, Irak1, and Rip2 are involved in response to A. fumigatus infection. Dectin-1 modulates the expression of Irak1 and Rip2. Additionally, these three signaling pathways are interconnected, and CLRs pathway plays a dominant role against A. fumigatus invasion.