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Deep brain stimulation versus ablative surgery for treatment-refractory obsessive-compulsive disorder: A meta-analysis.

Sarah Babette HagemanGeeske van RooijenIsidoor O BergfeldFrederike SchirmbeckPelle de KoningP Rick SchuurmanDamiaan Denys
Published in: Acta psychiatrica Scandinavica (2021)
This meta-analysis shows equal efficacy of ABL and DBS in the treatment of refractory OCD. For now, the choice of intervention should, therefore, rely on factors such as risk of developing impulsivity, patient preferences, and experiences of psychiatrist and neurosurgeon. Future research should provide more insight regarding differences between ABL and DBS and response prediction following direct comparisons between the surgical modalities, to enable personalized and legitimate choices between ABL and DBS.
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