The levels of TGFβ1, VEGF, PDGF-BB, and PF4 in platelet-rich plasma of professional soccer players: a cross-sectional pilot study.

Tomoharu MochizukiTakashi UshikiSatoshi WatanabeGo OmoriTomoyuki Kawase

Published in: Journal of orthopaedic surgery and research (2022)

TGFβ1, VEGF, and PDGF-BB levels in pro-athletes were not higher than those in non-athletes. These findings suggest that growth factor levels in PRP may not be a predominant determinant of the clinical effectiveness of PRP therapy in pro-athletes. Increased PF4 levels in pro-athletes suggest an immunological function of PRP that may positively influence tissue regeneration.

Keyphrases

platelet rich plasma
growth factor
stem cells
endothelial cells
randomized controlled trial
anti inflammatory
transforming growth factor
vascular endothelial growth factor
systematic review
smooth muscle
vascular smooth muscle cells
high school
epithelial mesenchymal transition
signaling pathway