A Systemic and Local Comparison of Senescence in an Acute Anterior Cruciate Ligament Injury-A Pilot Case Series.
Robert A WaltzKaitlyn E WhitneyVictoria R DukeHeidi KloserCharles HuardMatthew T ProvencherMarc J PhilipponChelsea S BahneyJonathan A GodinJohnny HuardPublished in: Life (Basel, Switzerland) (2023)
There is an abundance of senescent cells locally and systemically after an acute ACL tear without a significant difference between those present in peripheral blood compared to synovial fluid. This preliminary data may have a role in identifying strategies to modify the acute environment within the synovial fluid, either at the time of acute ligament injury or reconstruction surgery.
Keyphrases
- liver failure
- respiratory failure
- drug induced
- aortic dissection
- anterior cruciate ligament
- peripheral blood
- minimally invasive
- induced apoptosis
- clinical trial
- machine learning
- randomized controlled trial
- coronary artery disease
- electronic health record
- cell proliferation
- endothelial cells
- atrial fibrillation
- microbial community
- artificial intelligence
- deep learning
- wastewater treatment
- percutaneous coronary intervention
- mechanical ventilation
- cell death
- endoplasmic reticulum stress