Thyroid peroxidase (TPO) expressed in thyroid and breast tissues shows similar antigenic properties.
Marlena GodlewskaKatarzyna D ArczewskaMagdalena RudzińskaAnna ŁyczkowskaWanda KrasuskaKarolina HanusekJean RufMirosław KiedrowskiBarbara CzarnockaPublished in: PloS one (2017)
Expression of TPO in breast cancer together with its antigenic activity may have beneficial effects in TPOAb-positive breast cancer patients. However, further studies are needed to confirm the beneficial role of TPOAbs and to better understand the underlying mechanism.