Naltrexone augmented with prazosin for alcohol use disorder: results from a randomized controlled proof-of-concept trial.

Tracy L SimpsonCarol AchtmeyerLisa BattenJoseph ReouxJane ShoferElaine R PeskindAndrew J SaxonMurray A Raskind
Published in: Alcohol and alcoholism (Oxford, Oxfordshire) (2024)
These results suggest that prazosin augmentation of naltrexone enhances naltrexone benefit for alcohol use disorder. These results strengthen rationale for an adequately powered definitive randomized controlled trial.