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Intramolecular Hosomi-Sakurai Reaction for the Synthesis of Benzoxasiloles.

Xin-Long YuJia-Wei HuJian CaoLi-Wen Xu
Published in: The Journal of organic chemistry (2024)
A Lewis acid-catalyzed intramolecular Hosomi-Sakurai reaction of o -(allylsilyl)benzaldehyde/ketone has been developed. The reaction proceeds through simultaneous C-Si bond cleavage and C-C bond reconstruction. This protocol provides a rapid approach for the synthesis of allyl-substituted benzoxasiloles under mild conditions.
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