Systematic Assessment of 10 Biomarker Candidates Focusing on α-Synuclein-Related Disorders.
Isabel SchulzNiels KruseRoland G GeraThomas KremerJesse CedarbaumRobin BarbourWagner ZagoSebastian SchadeBirgit OtteMichael BartlSamantha J HuttenClaudia TrenkwalderBrit MollenhauerPublished in: Movement disorders : official journal of the Movement Disorder Society (2021)
Levels of most marker candidates tested in serum and CSF significantly differed between disease groups and HC. In the stratification of PD versus other tau- or aSyn-related conditions, CSF NfL levels best discriminated PD and MSA. CSF S100B and serum GFAP best discriminated PD and DLB. © 2021 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson Movement Disorder Society.