LncRNA ZFAS1 Alleviated NLRP3 Inflammasome-Mediated Pyroptosis through Regulating miR-96-5p/Smad7 Signaling in Allergic Rhinitis.

Jiabin ZhanYanyan QiYunlong FuJing ZhengJinli WuXin WeiMin Zeng

Published in: International archives of allergy and immunology (2024)

ZFAS1 downregulated the expression of miR-96-5p to upregulate Smad7 level, which subsequently inhibited NLRP3-mediated pyroptosis and inflammatory response to ameliorate allergic rhinitis.

Keyphrases

nlrp inflammasome
allergic rhinitis
epithelial mesenchymal transition
transforming growth factor
poor prognosis
oxidative stress