Is postmastectomy radiotherapy necessary for breast cancer patients with clinically node-positive downstaging to ypN0 after neoadjuvant chemotherapy?
Chen-Feng TanJun WangXiao-Rong ZhongZe-Lei DaiZhong-Zheng XiangYuan-Yuan ZengXiao-Yuan WeiNing-Yue XuLei LiuPublished in: Breast cancer research and treatment (2024)
In the context of comprehensive treatments, PMRT might be exempted in ypN0 breast cancer patients. Further large-scale, randomized controlled studies are required to investigate the significance of PMRT in this patient subset.
Keyphrases
- neoadjuvant chemotherapy
- locally advanced
- lymph node
- rectal cancer
- double blind
- squamous cell carcinoma
- sentinel lymph node
- open label
- radiation therapy
- placebo controlled
- case report
- early stage
- phase iii
- phase ii
- case control
- radiation induced
- breast reconstruction
- randomized controlled trial
- young adults
- study protocol