Improved clinical outcomes with early anti-tumour necrosis factor alpha therapy in children with newly diagnosed Crohn's disease: real world data from the international prospective PIBD-SETQuality inception cohort study.
Renz C W KlombergHella C van der WalMartine A AardoomPolychronis KemosDimitris RizopoulosFrank M RuemmeleMohammed CharroutJ C EscherNicholas M CroftLissy de Riddernull nullIvan D MilovanovichJames J AshtonPaul HendersonOren LedderTim G J de MeijRichard HansenThalia Z HummelKatsuhiro AraiAstor RodriguesFiona CameronSibylle KoletzkoRafeeq MuhammedNatalia NedelkopoulouPublished in: Journal of Crohn's & colitis (2023)
In this cohort of children with newly-diagnosed CD, early anti-TNF demonstrated superior effectiveness in high-risk patients.