Involvement of GPR43 Receptor in Effect of Lacticaseibacillus rhamnosus on Murine Steroid Resistant Chronic Obstructive Pulmonary Disease: Relevance to Pro-Inflammatory Mediators and Oxidative Stress in Human Macrophages.
Ana Karolina SáFabiana OlímpioJéssica Aparecida VasconcelosPaloma Cristina RosaHugo Caire Faria NetoCarlos Rocha OliveiraMaurício Frota CamachoUilla BarcickAndré ZelanisFlávio AimbirePublished in: Nutrients (2024)
Lr attenuates lung inflammation and oxidative stress in COPD mice, suggesting the presence of a GPR43 receptor-dependent mechanism also found in macrophages.
Keyphrases
- oxidative stress
- chronic obstructive pulmonary disease
- lung function
- dna damage
- endothelial cells
- diabetic rats
- ischemia reperfusion injury
- induced apoptosis
- fatty acid
- induced pluripotent stem cells
- binding protein
- type diabetes
- high fat diet induced
- metabolic syndrome
- skeletal muscle
- signaling pathway
- air pollution