Cirrhosis Regression is Associated with Improved Clinical Outcomes in Patients with Nonalcoholic Steatohepatitis.

Arun J SanyalQuentin Mark AnsteeMichael TraunerEric J LawitzManal F AbdelmalekDora DingLing HanCatherine JiaRyan S HussChuhan ChungVincent Wai-Sun WongTakeshi OkanoueManuel Romero-GomezAndrew J MuirNezam H AfdhalJaime BoschZachary GoodmanStephen A HarrisonZobair M YounossiRobert P Myers

Published in: Hepatology (Baltimore, Md.) (2021)

In patients with compensated cirrhosis due to NASH, regression of fibrosis is associated with a reduction in liver-related complications. These data support the utility of histologic fibrosis regression and NITs as clinical trial endpoints for NASH cirrhosis.

Keyphrases

clinical trial
risk factors
randomized controlled trial
study protocol
machine learning