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The prognostic relevance of FOXA1 and Nestin expression in breast cancer metastases: a retrospective study of 164 cases during a 10-year period (2004-2014).

Shahin De LaraJenny NyqvistElisabeth Werner RönnermanKhalil HelouElisabeth Kenne SarenmalmZakaria EinbeigiPer KarlssonToshima Z ParrisAnikó Kovacs
Published in: BMC cancer (2019)
In our study, FOXA1 was expressed mostly in ER-positive breast cancer metastases. Expression of Nestin was related to triple-negative metastases, where brain was the most frequent metastatic site. These findings highlight the clinical utility of FOXA1 and Nestin expression and warrant their inclusion in routine immunohistochemical panels for breast carcinoma.
Keyphrases
  • poor prognosis
  • positive breast cancer
  • small cell lung cancer
  • binding protein
  • long non coding rna
  • resting state
  • functional connectivity
  • breast cancer cells
  • childhood cancer