HIV viral kinetics and T cell dynamics in antiretroviral naïve persons starting an integrase strand transfer inhibitor and protease inhibitor regimen.

Maile Y KarrisSonia JainTyler R C DayJosué Pérez-SantiagoMiguel GoicoecheaMichael P DubéXiaoying SunCelsa SpinaEric S DaarRichard H HaubrichSheldon Morrisnull null

Published in: HIV clinical trials (2017)

The prolonged first phase viral decay observed with RAL + LPV/r in persons starting ART did not result in differences in viral suppression at week 48. We also observed trends in declines in certain cellular markers of immune activation but it remains unclear if this could translate to long-term immunologic benefits in persons on an INSTI + PI.

Keyphrases

hiv infected
sars cov
antiretroviral therapy
human immunodeficiency virus
hiv positive
hiv aids
hiv infected patients
hepatitis c virus
hiv testing
men who have sex with men
randomized controlled trial
clinical trial
south africa
placebo controlled