Markers of disease activity in COPD: an 8-year mortality study in the ECLIPSE cohort.
Bartolome R CelliNicholas LocantoreJulie C YatesPer BakkePeter M A CalverleyCourtney CrimHarvey O CoxsonDavid A LomasWilliam MacNeeBruce E MillerHana MullerovaStephen I RennardEdwin K SilvermanEmiel WoutersRuth Tal-SingerAlvar AgustiJorgen Vestbonull nullPublished in: The European respiratory journal (2021)
In COPD, 1- and 3-year changes in exacerbation frequency, systemic inflammation, BODE and SGRQ scores and FEV1 decline are independent markers of disease activity associated with 8-year all-cause mortality. These disease activity markers are generally independent and not predictable from baseline measurements.
Keyphrases
- disease activity
- systemic lupus erythematosus
- rheumatoid arthritis
- chronic obstructive pulmonary disease
- rheumatoid arthritis patients
- ankylosing spondylitis
- juvenile idiopathic arthritis
- lung function
- type diabetes
- cardiovascular events
- risk factors
- cystic fibrosis
- cardiovascular disease
- intensive care unit
- coronary artery disease
- air pollution
- mechanical ventilation