Transcriptome analysis reveals SALL4 as a prognostic key gene in gastric adenocarcinoma.

Ranjan Jyoti SarmaSarathbabu SubbarayanJohn ZohmingthangaSaia ChenkualThomas ZomuanaSailo Tlau LalruatfelaJeremy L PautuArindam MaitraNachimuthu Senthil Kumar

Published in: Journal of the Egyptian National Cancer Institute (2022)

Upregulation of APOC1 is associated with marginal overall survival (OS) and SALL4 over-expression was associated with the poor OS using KM-Plotter during 5 years data period. Our study suggests that SALL4 could be a promising biomarker candidate in STAD.

Keyphrases

poor prognosis
squamous cell carcinoma
cell proliferation
electronic health record
genome wide
copy number
signaling pathway
big data
gene expression
locally advanced
binding protein
genome wide identification
data analysis