Downregulated PRNP Facilitates Cell Proliferation and Invasion and Has Effect on the Immune Regulation in Ovarian Cancer.

Kuan Hu Xiaofang Zhang Lei Zhou Juanni Li

Published in: Journal of immunology research (2022)

This study demonstrated for the first time showed that ferroptosis-related gene PRNP exerted a tumor suppressive role in OC and the aberrant expression and function of PRNP making it a potential novel biomarker for OC diagnosis, prognosis, and response to immunotherapies.

Keyphrases

poor prognosis
single cell
cell therapy
genome wide
copy number
binding protein
human health
long non coding rna
mesenchymal stem cells
risk assessment