Gingival tissue samples from periodontitis patients demonstrate epithelial-mesenchymal transition phenotype.

Saif S SaliemSalwan Y BedeAli Abbas AbdulkareemBashar H AbdullahMichael R MilwardPaul R Cooper

Published in: Journal of periodontal research (2022)

There were marked downregulation of epithelial molecules and upregulation of mesenchymal markers in gingival tissues derived from periodontitis patients, suggesting expression of the EMT phenotype in the pathological epithelial lining of periodontal pockets.

Keyphrases

epithelial mesenchymal transition
end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
poor prognosis
signaling pathway
stem cells
cell proliferation
gene expression
bone marrow